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ZytoLight ® SPEC NRG1 Dual Color Break Apart Probe
ZytoLight ® SPEC NRG1 Dual Color Break Apart Probe

ZytoLight ® SPEC NRG1/CD74 TriCheckTM Probe

The ZytoLight SPEC NRG1/CD74 TriCheckTM Probe is designed to detect translocations involving the NRG1 gene and the CD74 gene. Using this probe it is possible to discriminate between CD74-NRG1 fusions and translocations affecting NRG1, but not CD74, such as SLC3A2-NRG1 or VAMP2-NRG1 fusions detected in various tumors. NRG1 fusions constitute a good candidate for potential therapeutic applications.

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